Serotonin vs dopamine adhd reddit. Still, if they work for you, that’s totally fine.
Serotonin vs dopamine adhd reddit SSRI work in very similar way to Ritalin as they block the re uptake of serotonin; while Ritalin stops dopamine. Methylphenidate works well for the former, and also increases the firing rate and communication of neurons (more speedy for the brain) while the latter is more effective at increasing monoamine levels via TAAR1 agonism (efflux) and VMAT2 inhibition (reuptake inhibition via reversal Nov 13, 2024 · What role does serotonin play in attention-deficit hyperactivity disorder (ADHD)? Serotonin generally operates within a complex network of brain regions, including the frontal cortex, limbic system, basal ganglia, and reticular activating system, which are usually involved in attention and emotional control, as well as impulse control. Do you your own research. I just wonder if someone is dopamine depressed wouldn't that be same ADHD/ADD? The MCAT might not get this specific but in regards to sleep, low concentrations of serotonin are seen during REM sleep and one of the reasons why some people taking an SSRI have trouble falling asleep is because high levels of serotonin can inhibit REM sleep. It can kill you. I've noticed verbal fluency has tremendously increased as has my drive to be social and completing tasks feels far more simple instead of an insane hyperfocus. It is a serotonin releaser (increases the serotonin secretion), which targets 5HT-1A receptors (among many other targets), which are located in high density in the amygdala. Serotonin only uses a kernel exploit to my knowledge, which only makes it a semi-jailbreak. Regular exercise has been shown to increase both serotonin and dopamine levels, contributing to improved mood and motivation. It's a dopamine reuptake inhibitor. Serotonin is not a "feel good chemical" it is a neurotransmitter with an absolutely massive list of functions. Dopamine is made into norephinephrine (insufficiency in some people leads to depression or ADHD), which, in turn, is made into epinephrine. Memory and Learning. Members Online Ok_Ad_2562 Hello reddit. 14 votes, 16 comments. way to boost dopamine and serotonin. Yes!! For years when I was in the pit of my "depression" I would spend hours masturbating over and over again just to bring some dopamine to my sad life. Since these imbalances are what caused the depression or anxiety, depression would not affect the levels of serotonin and dopamine. Notably, when there is both reuptake inhibition and release occurring simultaneously, there are contradictory effects depending on the ratio of reuptake/release. Doing a "fast", for which there is no scientific support, serves no purpose if your adhd isnt treated properly. I actually have my next appointment this Wednesday and am hoping my doc will I like to find out if my levels of serotonin and/or dopamine are not in balance. Wellbutrin -Bupropion , all things related to this antidepressant. This intricate balance may explain why some individuals respond better to certain treatments than others. it’s why ssris increase rls, adhd sx, decrease motivation, sex drive, etc for some reason this is never brought up when adhd folk get prescribed antidepressants??? i was pissed at my psychiatrist when i researched this after starting lexapro and The meds people are given for ADHD do release norepinephrine, there are 2 main ADHD drugs/drug classes amphetamines and methylphenidate. MDMA on the other hand releases mostly serotonin and norepinephrin. Before that people thought that bipolar was related to issues with bile. Also between the two periods we had things like lobotomys routinely going on until as recently as 1980. I truly believe that serotonin can be harmful if too high compared to dopamine, personally felt awful until I took serotonin blockers. A reddit discussion from some years had a post saying it increases dopamine and is a serotonin antagonist. Now that I have this knowledge, I'm going to stop taking the supplements for (what I now assume to be inaccurate) low serotonin levels, and experiment with supplements that help the body synthesize dopamine, such as L-Tyrosine. Long story short, all that stuff about how you get a dopamine rush from video games, or that relaxing music is good for your serotonin levels, is 100% grade A unpasteurized bullshit. Doing all the things you describe are great but you can't say one single action effects Serotonin in such a cause effect manner like weight lifting, that's The closest serotonin "analog" I can think of to amphetamine would be MDMA, although this is not a perfect analogy by any means. Now it does not mess with dopamine in the same way, but just like Abilify is a dopamine specific modulator at some doses it stimulates dopamine, some it suppresses, and some it modfies specific receptors we recently approved a serotonin moddulator that does similar types of things but with sertonin neurotransmitters instead of dopamine named If I take too much ritalin (which boosts dopamine levels - I have ADHD), I get OCD, rigid, and inflexible (symptom of low serotonin, dopamine dominance). Dopamine, tends to be the one elevated during manic phases of bipolar disorder. Dopamine is also involved in attention, perception, motor function, and memory formation. That lack of satisfaction is stored, marking the memory as unimportant. Never take 5-htp alone for very long, it raises serotonin and it can have nasty life altering side effects if you don't balance it with a dopamine enhancer. We can try to manipulate serotonin leves through various means such as: Serotonin releasing drugs (most of these fall into the illicit-but-can-be-fun category) Serotonin reuptake inhibitor drugs (which can have good, bad or mixed results) It might not help ADHD to 'increase dopamine in the synapse' if it is taken back up into the synapse so fast. Right now im going with protein drinks eith a lot of amino acids, mucuna pruriens for dopamine,black seed oil for I guess general healing and mood lift,I was mainly trying to figure out the seretonin one as reviews had mixed results on htp 5 I read there were blood test to check dopamine levels but eith a quick google couldnt find one for only on ADHDtok I came across a video quoting this: https://pubmed. look up the reddit Nov 7, 2024 · This can lead to low levels of dopamine and contribute to symptoms of ADHD. Serotonin, when dealing with mental illness, has more to do with the number of receptors for serotonin. Insufficient serotonin can be linked to poor sleep, as it leads to insufficient melotonin. Learned this the hard way recently when my Dr's were clueless, knew I was taking 5-HTP morning and night and after 2 years I got really high blood pressure and bipolar like symptoms from Yeah whenever I’ve seen folks mention their experiences with Wellbutrin on Reddit it’s like 50/50 as far as loving it vs having bad affects. Thats why people with adhd can get easily hooked to social media, video games ect. Hence we need more neurotransmitter precursors than the average person. That means you will stock the outlet, the cannon if you like with even more dopamine. r/depressionregimens is a community focused on the research and… Dopamine similarly is involved in many behaviours so it’s hard to understand exactly what it does. I understand for at least the most part that adhd is caused by a dopamine imbalance/dysfunction. However I was wondering to what extent serotonin plays in the condition, given its varied complex role and wide distribution I would of guessed it had some role Aug 4, 2024 · The balance between dopamine, serotonin, and norepinephrine is likely critical in the manifestation of ADHD symptoms. An addict will get hit with a tactical nuke of dopamine upon the slightest whiff of their substance/experience of abuse, yet even when they consume that substance/experience, they may not experience pleasure. So they deplete dopamine. "). Or being immune against SSRI side effects if you have a depression. Aug 22, 2024 · Attention Deficit Hyperactivity Disorder (ADHD) is another condition associated with dopamine dysfunction. Dopamine plays a crucial role in attention and working memory, helping you focus and manipulate information. So I have really bad depression, anxiety and ADHD. Depression is caused by your brain not absorbing as much serotonin as a normal brain, ADHD is caused by your brain not absorbing dopamine. Dopamine is released in conjunction with your body's movement towards acquiring something (food, sex, water, drug). Dopamine makes you do things in order to be happy. Community for autistic people with ADHD to ask advice, vent about your day, share stories, infodump on your special interests and most importantly: be yourself. Not serotonin. Also while antidepressants usually work on a serotonin level, stimulates work more on a dopamine/Noradrenaline level. SSRIs tend not to exacerbate ADHD symptoms, though it isn't impossible for them to cause a decrease in motivation. Serotonin is more euphoric and feels better than dopamine, it's like comparing speed (dopamine) to MDMA(serotonin), MDMA is more enjoyable by far, a lack of it is hell and a risk for suicide more than dopamine. we don't know whether depression is caused by a lack of serotonin or dopamine or both. Thus, the binding of dopamine to these particular receptors inhibits the pre-synaptic release of dopamine. Focusing on self-care and attending to the needs of others is extremely settling. L-phenylalanine has to be turned into L-Tyrosine, which has to be turned to L-Dopa, which is then turned into dopamine. Engage with friends. I set aside time at work to work on problems which may yield "interesting" results. You have to find a way to focus on serotonin-producing activities vs primarily dopamine-generating activities. This only starts happening when you’ve had So to recap: Greater substrates for neurotransmitters from amino acids for dopamine and serotonin ** Likely directly accounting for a micronutrient deficiency or down-stream imbalance to cause the improvements ** Greater blood sugar regulation from protein as primary macronutrient in a meal vs. Sep 18, 2023 · Serotonin is associated with feelings of happiness, focus, and calm, whilst dopamine is associated with feelings of rewards, motivation, and productivity. Norepinephrine–dopamine reuptake inhibitor (NDRI) , major depressive disorder, atypical antidepressant , Epileptic seizures , ADHD, alleviate sexual dysfunction, weight loss, releasing agent of dopamine and norepinephrine (NDRA), similarly to other cathinones , Wellbutrin SR and XL The causes of most mental health problems are poorly understood and the involvement of neurotransmitters like dopamine and serotonin is inferred only by indirect evidence. There was a theory at one point that SSRIs actually work by increasing dopamine indirectly—basically, when you have higher serotonin concentrations in the brain, the serotonin starts hijacking dopamine transporters to carry the extra serotonin away, which means you start getting higher dopamine. That's like saying having anxiety makes you immune against benzos horrible side-effects. Aug 22, 2024 · Similarly, foods high in tyrosine, like almonds, avocados, and bananas, can boost dopamine levels. While Ritalin (methylphenidate) is a norepinephrine (and dopamine) reuptake inhibitor. Ive recently switched to a antidepressant that focuses on dopamine as opposed to serotonin and have noticed really awesome results. It's why MDMA is such a popular drug. you are correct that one of the genetic conditions of adhd is lack of dopamine. Feeling worthless or losing (losing a fight or a sports game for example) will often cause lowered serotonin as well. Most ADHD meds, or coffee in your case, cause the synthesis of dopamine, along with serotonin and norepinephrine. When you have ADHD, your brain doesn't keep enough dopamine floating in that particular pathway, which means you don't feel satisfaction when doing things that would normally be rewarding. The Dopamine-Serotonin scenario you describe is ludicrously over simplified. Plus they have different roles in different parts of the body, and even in different areas of the brain. Zyban. Its mostly that you will function more well of a adhd medicine than someone who doesn't have adhd. All of us would have been classified as ADHD today. They might be better for people with addictive personalities. For example, when you listen to music you like, dopamine as well as serotonin and other neurotransmitters are released making you want to listen to the music again. Serotonin was nice too, but tweak injection + bootstrap on every app = you were duplicating bundles (meaning doubling the app bundle and losing space) not to mention, if you wanted system wide tweak like (keyboard) you will need to inject into all apps— which is extremely dangerous n losing massive space — for what just to Dopamine reuptake inhibitors, on the other hand, are unable to cause euphoria, even if they are injected in very high doses. The last 4 months my therapist recommend that i would try dexamphetamine, in my case Tentin. So, supplementing L-phenylalanine won't significantly raise dopamine, since it's a distant precursor. Serotonin binds to this receptor, which inhibits these neurons from releasing dopamine and/or norepinephrine. Dopamine 2 is much safer and better as it’s a full on jailbreak. The Wikipedia page says it doesn't affect either serotonin or dopamine. Serotonin vs Dopamine When you practice mindfulness and appreciate every little thing in your life as a blessing you will be more content and happy hence your brain releases serotonin. I seem to have inherited some of the same genes. Still, if they work for you, that’s totally fine. Having adhd doesn't make you immune to the side effects at all. I (27f) deal with ADHD, anxiety, and depression - all unmedicated. Lions mane causes the expression of neuronal growth factor, which is associated with increased/enhanced acetylcholine function in the hippocampus. Serotonin makes you happy after you do those things. Anyone got further research or info on this theory? I do not think it is far A couple days ago I started taking my serotonin supplements again, mainly because I forgot I had stopped taking it. Dopamine and serotonin are considered the ‘ happy hormones ’ as they increase positive moods and emotions. had me on. So, it gets used up. Dopamine releasers work great for ADHD, but some people might have a problem with them since they can lead to addiction to the euphoric effects. Serotonin has an inhibitory effect in dopaminergic pathways (mesocorticalimbic, substantia nigra), decreasing dopamine in the brain. I love solving "problems/puzzles"; it's a key part of my ADHD, gives me a huge dopamine rush. *dopamine I'm hopped on sugar, I've got all the music blaring, I'm dressed to the nines and it's not working. it also inhibits norepinephrine pathways, and testosterone. You can buy it as B6 and l St. It fills a gap. serotonin. The avalanche of dopamine can actually be incredibly uncomfortable. But with high dopamine my oh my. https://pubmed. When looking at most information about ADHD, its treatments and causes the main neurotransmitters discussed and involved are dopamine and norepinephrine and I understand why of course. Wellbutrin was the first thing that made even a slight dent in my brain fog and malaise (an SNDI, it works on norepinephrine and a little bit on dopamine instead of serotonin). ncbi. So it’s possible that increasing dopamine levels can help reduce ADHD symptoms. You feel serotonin after having sex (when it's good). However there are some medications such as strattera (aka atomoxetine) that alleviate adhd in some by increasing norepinephrine levels. Low serotonin often makes people feel worthless. Switch off one group of dopamine neurons, and you can't move (Parkinson's disease). I now have my anxiety totally covered (bromazolam, rc benzo) and less than a month ago I was finally prescribed Vyvanse which definitely helps the ADHD but also really helps my depression, due to the dopamine release. They also confuse the reinforcing properties of dopamine with serotonin action. And the question is, will any more dopamine be emitted is the warehouse if over-full. gov/9342764/ Treat depression (serotonin 🆙) ADHD gets worse (dopamine down⬇️) and vice versa. These common neurotransmitters act on similar parts of the body but have different effects on mood and memory, digestion, and other functions. Impulsive behaviour went way up and I developed hypochondria. The result of a multi-decade marketing campaign by drug makers trying to simplify things for a TV audience, and a good-faith effort by psychiatrists trying to condense 8+ years of schooling into a two minute soundbite for consumption by their patients, has resulted in the general public accepting an explanation of dopamine, serotonin, and the rest that is self-contradictory and simply doesn Satisfaction. Dec 10, 2024 · Serotonin and dopamine are neurotransmitters, the chemical messengers that allow nerves to communicate with each other or with other structures in your body. In some pathways in the brain, serotonin and dopamine have antagonistic effects. Serotonin is made into normelatonin, which is made into melatonin. when I took it and they doubled my dose to 300mg I started having what I thought were “rage attacks” but later I discovered I’m autistic and Wellbutrin or it’s side effects or something triggered my autistic meltdowns more than anything else. If dopamine was a pleasure chemical, this would not happen. 78 votes, 133 comments. Not only does amphetamine have affinity for dopamine, noradrenaline and serotonin reuptake, but it also facilitates the release of each of them. The "high" from speed is the massive release of dopamine, and amphetamines as far as i know do release a greater amount of dopamine than MDMA, as well as slightly less norepinephrin and little serotonin. Serotonin: Sunlight, exercise, diet, meditation and relaxation (not partying to relax), and volunteering activities. nih. Amphetamine is primarily a dopamine releasing agent and MDMA is primarily a serotonin releasing agent, although both drugs have some activity at other receptors as well. Never knew it was because of my adhd till I started learning more about it. I myself have started taking DL-Phenylalanine two weeks ago, and haven't noticed anything indicating I have higher dopamine. An article in Brain basically had a conclusion of different gray matter, not dopamine. Now, MDMA is its own interesting case. serotonin and dopamine are in a feedback loop where increasing serotonin decreases dopamine. I have been treated with medication for depression and ADHD simultaneously and the results were disastrous. Dopamine is far more than reward, 1) it is also aversion as in approach and withdrawl , 2) it is also purposefully reducing noise in the prefrontal cortex via D1 dopamine receptors, 3) it is also fine tuning emotional, cognitive, and motor behavior via the striatum, and it is the 4) regulation of many hormones that What surprises most people is that serotonin isn't produced in the brain, This isn't exactly true. Dopamine and Serotonin play a role in our moods and feelings. Moreover, the relationship between serotonin and other neurotransmitters like norepinephrine and oxytocin in ADHD is an area of ongoing research. EDIT: serotonin can also be thought as primarily an inhibitory neurotransmitter in the CNS. This interaction can influence dopamine release and reuptake, potentially affecting ADHD symptoms. Was just wanting to hear of some similar experiences people have had with this? Sorry for the drawn out post. heyyy borderline and adhd person here so i know what u mean trying to distinguish them lol in my experience euphoria from bipolar feels more of a general sense of i’m okay as well as high mood meanwhile if it’s more temporary like from adhd or borderline i usually still know and recognize the fact my life sucks but i still feel on top of A partial agonist can also function as an antagonist SOMETIMES: For example, if there's LOTS of serotonin being released, and a partial agonist (which binds to the same site on the receptor as serotonin, but doesn't activate the receptor as fully as serotonin does) gets introduced, some receptors that WOULD have been fully activated by SSRI’s hijack dopamine receptors and turn them into serotonin receptors. However, this doesn't mean that serotonin is simply the opposite of dopamine. John's wort extract has a clear inhibitory effect on the neuronal uptake not only of serotonin, noradrenaline, and dopamine but also of gamma-aminobutyric acid (GABA) and L-glutamate. Potentially improved gut microbiome. ADD meds focus on dopamine reuptake. Most of the anti depressants that have been around for a long time increase serotonin, but some newer ones work to increase dopamine instead. There are several natural ways to boost serotonin and dopamine levels. ; Serotonin is vital for activating the hippocampus, crucial for forming long-term memories. Dopamine is released from two different areas: the substantia nigra, and the ventral I've also suffered from both serotonin and dopamine depression (most antidepressants only focus on serotonin). Dopamine does not cross the blood-brain barrier Neither does Serotonin. I have tried L-Tryptophan and L-Tyrosine for weeks one after the other, but both supplements are extrem subtle for me and my anxiety, i couldnt find any single reliable difference (i have used all co factors). Dopamine: Gaming, sex stuff, junk Low dopamine often makes people hyper, because wild movement increases dopamine levels. I am sorry but your understanding of dopamine is very basic and thus is wrong. So SSRIs may be helpful if you also have depression, but they will not help much with ADHD. "Together, they discovered that it’s not a coincidence that people binge on carbohydrates when they want to lift their mood. It is an excellent question because these two chemicals share a lot of responsibility for how you feel, think, and act. I just cannot fucking function and I h a t e it. Serotonin has less energy behind it, and often it's more about the modification of what you're perceiving. No other antidepressant shows an approximately equally broad inhibitory profile. This can give them undesirable side effects. To say that happiness is even mostly about the balance of just these two neurotransmitters is patently untrue. I would ask for serotonin but, as previously mentioned, SSRI's weren't quite doing the job enough, and as far as I know they don't play a role in dopamine release. I have never felt so good in my life compared to using methylphenidate. Many ADHD medications work by increasing dopamine levels or enhancing its signaling in the brain, which helps improve focus and reduce impulsivity. My father has ADHD and also a genetic defect which seems to cause low dopamine levels and he now has Parkinson's, which is caused by a longterm lack of dopamine in the brain. DL-phenalyaine. About 80-90% of our serotonin IS produced in the gut, but it mostly stays in the rest of your body. yes. We do NOT promote drug use; - Accept, for better and or worse, that licit & illicit drug use is part of our world and choose to work to minimize its harmful effects rather than simply ignore or condemn them; - Utilize evidence-based, feasible, and cost-effective practices to prevent and reduce harm; - Call for the non-judgmental, non-coercive provision of services and resources to people who My point is that it is not dopamine that makes us happy, it is the hedonic hot spots (to the best of our understanding). Gotu kola: can boost dopamine, but also serotonin Saffron extract Uridine: repairs dopamine receptors Black hoof mushroom extract: supposedly lowers serotonin, I use it for an energy boost too Cordyceps: May have a low dopamine boost Schisandra: serotonin antagonist, also lowers excess estrogen I don’t use all of these daily. Given that I am ADHD I realized that Bupropion may be a better option for me than the Lexapro my Dr. As far as depression goes. The most widely used ADHD medications work by increasing dopamine levels in the brain. Since methylphenidate does however, I'm assuming dopamine is what my brain is lacking that's making me so anxious/sad. It's got me thinking about long term effects. The affect that serotonin has on happiness was drawn from the idea that SSRI's increase serotonin in the synaptic cleft, and reduction in depressive symptoms seem to occur over the long-term. Look, for me boosting my dopamine, my serotonin, my adrenaline and keeping the levels stable makes me feel amazing, than I lower my adrenaline at night with benzos then boost it again in the morning with ephedrine, my high serotonin should convert to high level of melatonin which is a powerful antioxidant Dopamine also has a PPL (combined with PAC) bypass, which combined with a kernel exploit (kfd) allows for a full jailbreak. Sabroxy doesn't make more of anything, it just increases the amount of time dopamine hangs around outside of neurons. This review states that there's increased dopamine transporter availability in humans who have used amphetamine at therapeutic doses ("Imaging studies of ADHD-diagnosed individuals show an increase in striatal dopamine transporter availability that may be reduced by methylphenidate treatment. Neither really affects dopamine or serotonin levels except in the most indirect, downstream ways. I tried Trazadone for anxiety and sleep and got that. As far as I can understand, what happens is that increased concentrations of serotonin mean that dopamine receptors will be activated by the serotonin. If I keep building tolerance to the medication, and my brain keeps adjusting its equilibrium level of dopamine to compensate, doesn't it seem like stimulants are useless as a long term solution? When I think about SSRIs, they increase the equilibrium level of serotonin in the brain. I have so much work to do and I just can't pull myself together. This is why a common symptom of SSRIs is reduced sex drive. is your friend. carbs or fat. [8][9][10] As such, it has been suggested that clinically it may weakly inhibit the reuptake of dopamine,[11] particularly at high dosages. Because i also suffer from depression, i have always lacked dopamine and serotonin. [1] Can Increasing Dopamine Levels Help ADHD? ADHD and dopamine deficiency are linked. Dopamine is important in the reward system. It is, also, associated with obsessiveness and goal directed behavior. Any depression would be caused by imbalances of Serotonin and Dopamine uptake and re-uptake. Switch off another, and you start lactating (yes you read that right). But adderall is what really changed the game and has allowed me to be a halfway functional human. Norepinephrine–dopamine reuptake inhibitor (NDRI) , major depressive disorder, atypical antidepressant , Epileptic seizures , ADHD, alleviate sexual dysfunction, weight loss, releasing agent of dopamine and norepinephrine (NDRA), similarly to other cathinones , Wellbutrin SR and XL All I wish for is a little bit more naturally released dopamine. Jan 21, 2025 · Perhaps you have searched for clarity around serotonin versus dopamine or dopamine versus serotonin, hoping to understand if one neurotransmitter drives joy while the other fuels ambition. I believe that there are two theories for adhd, rapid reuptake of monamines and low concentrations of monoamines. Basically, in addition to everything everybody else has posted, there's a fundamental difference between dopamine and serotonin. gov/9418743/ stating “SSRI’s have not been tested in controlled trials, but they can cause inconsistent changes, often aggravating ADHD symptoms” I’ve tried to do more research on sertraline’s affect on dopamine but I’m finding conflicting information. But amphetamine blocks some re-uptake and activates release of serotonin (not too much but some), norepinephrine (remember synthesized from dopamine) and dopamine. Serotonin (SE) may also play a small role, but that is an area of active research with even less scientific understanding. I tried a lot of ADD and anti-depressant meds. Aug 4, 2024 · For instance, serotonin interacts with dopamine, another key neurotransmitter implicated in ADHD. In the absence of depressive symptoms, it would seem that happiness MUST be increasing because of increased extracellular serotonin, right? I was diagnosed with a gene of a serotonin deficiency in my receptors I’ve learned that for people with this it’s hard to regulate your own moods if something upsets me my obsessive thoughts start to happen and I can’t really control where those thoughts lead most of the time if it upsets me enough I go into a kinda of shut off state I've seen some mention of Metadoxine having the effects you want but it is a bit controversial it seems. Oh, my siblings. It also has some role in Parkinsons, but thats completely different pathway in the brain. Well it says so on Wikipedia, with a good amount of literature references; "Sertraline (Zoloft) is a selective serotonin reuptake inhibitor (SSRI), but, uniquely among most antidepressants, it shows relatively high (nanomolar) affinity for the DAT as well. Norepinephrine plays some sort of role in both depression and ADHD, but we’re not entirely sure what. " This is classic dopamine incentive motivation triggering. . Aug 4, 2024 · While dopamine has long been considered the primary neurotransmitter involved in ADHD, recent research has shed light on the important role of serotonin in modulating dopamine function and influencing ADHD symptoms. Then you have the D2 receptor, which acts as an autoreceptor (typically in one of its two isoforms) when expressed presynaptically. And when I take tryptophan (to raise serotonin), it works (I get very sociable/happy/good mood/flexible), but then my ability to focus seems to deteriorate (lowered dopamine, serotonin dominance). They may have similar symptoms but those with ADHD will have low dopamine while those with OCD will have low serotonin. I don't know anything about your particular med but serotonin syndrome is dangerous. I don't think that's how I would read the papers I've managed to find. In fact, many types of depression are cause by an excess of serotonin and dopamine uptake. Amphetamine (speed) by itself affects mostly dopamine and norepinephrin. Stimulant medications work to correct this deficiency. [12] The dopamine and serotonin theories were developed a very long time a go now and most likely aren't worth their weight. i can see why people with adhd have higher rates of substance abuse because hoooolllly shit I would be willing to try a LOT of stuff to get out of this headspace. 50K subscribers in the depressionregimens community. This suggests that Ritalin will reduce your overall dopamine production long-term to compensate the reduction or the inhibitation of dopamine reuptake. When you don’t and indulge in self loathing and regret and negative emotions you desire a fix, an escape from reality hence you crave dopamine and fap to get Mine (ritalin) works on dopamine, not serotonin but I get serotonin syndrome like symptoms from other meds. Serotonin seems to impact dopamine signally as well, so drugs that increase both dopamine and serotonin tend to have a mixture of both wanting but also feeling satisfied. The two most important neurotransmitters that are thought to be involved in ADD/ADHD are dopamine (DA), and norepinephrine (NE). Specifically adderall (amphetamine) is a norepinephrine (and dopamine) releasing agent. nlm. As adhd is mainly a neurotransmitter problem, stimulates should work more directly on the root cause of the problem than antidepressants. Now anytime I masturbate during the day for a dopamine hit it like triggers this really horrible time in my life. I’ve seen a few times in this community that people really push the ‘dopamine deficiency’ and it’s a bit of a pet peeve of mine as a scientist - Whilst there is evidence to suggest that dopamine is involved, we certainly don’t have enough of it to be able to go around saying that ADHD is rooted in dopamine deficiency. It is released when you anticipate something and triggers your behaviour to get the reward. Therapeutic approaches targeting the dopamine system vary depending on the specific disorder. sqyxurdt wbku pdapn nkkje qbha pdzq foebbn pzypow ddplt mwyyh ylocz ibhvw lfqabb lblog fsnv